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Research

Identification of subgroups of children in the Australian Autism Biobank using latent class analysis

The identification of reproducible subtypes within autistic populations is a priority research area in the context of neurodevelopment, to pave the way for identification of biomarkers and targeted treatment recommendations. Few previous studies have considered medical comorbidity alongside behavioural, cognitive, and psychiatric data in subgrouping analyses.

Research

Clinical Trials in the Brain Tumour Population: Challenges and Strategies for the Future

This review identifies challenges and barriers to successful development of drugs in neuro-oncology trials at the preclinical, clinical and translational stages that we believe has contributed to poor outcomes for patients over the last 30 years.

Research

Individual-Level Risk and Resilience Factors Associated with Mental Health in Siblings of Individuals with Neurodevelopmental Conditions: A Network Analysis

Siblings of individuals with neurodevelopmental conditions (NDCs) are exposed to unique family environments and experience a range of psychosocial risk and resilience factors.

Research

Harnessing neuroplasticity to improve motor performance in infants with cerebral palsy: A study protocol for the GAME randomised controlled trial

Cerebral palsy (CP) is the most common physical disability of childhood worldwide. Historically the diagnosis was made between 12 and 24 months, meaning data about effective early interventions to improve motor outcomes are scant. In high-income countries, two in three children will walk. This evaluator-blinded randomised controlled trial will investigate the efficacy of an early and sustained Goals-Activity-Motor Enrichment approach to improve motor and cognitive skills in infants with suspected or confirmed CP.

Research

Surgery for rheumatic heart disease in the Northern Territory, Australia, 1997-2016: what have we gained?

Between 1964 and 1996, the 10-year survival of patients having valve replacement surgery for rheumatic heart disease (RHD) in the Northern Territory, Australia, was 68%. As medical care has evolved since then, this study aimed to determine whether there has been a corresponding improvement in survival.

Microscopy and Imaging

The Kids Research Institute Australia is equipped with a diverse range of histology and microscopy equipment and analysis software to facilitate state-of-the-art imaging.

Laboratory Equipment

Most laboratory equipment at The Kids Research Institute Australia is owned and maintained by the Institute, in order to make this available for use by all staff and students.

Revolutionising diabetes management for children and families

Imagine living with a condition that requires you to make approximately 180 health- related decisions every day for the rest of your life.

Community voices to foster cultural safety

Life imitates art in a new project that seeks to entrench cultural safety for young Aboriginal and Torres Strait Islander people into WA’s mental health system.

Difficult journey for Tahlea after fight back from disease

At just six months old, Tahlea Dalgety was flown from Geraldton to Perth with a slim chance of survival after contracting meningococcal disease.