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Research

Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis

The aim of our study was to characterize the activity of TNAP on TLR agonists and assess the concentrations of plasma ALP during late-onset sepsis in newborns.

Research

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation.

Research

A prospective audit of pain profiles following general and urological surgery in children

To determine the duration and severity of acute postoperative pain experienced by children undergoing 8 different general and urological procedures.

Research

Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology

Lack of agreement about criteria and terminology for children's language problems affects access to services as well as hindering research and practice.

Research

Early life innate immune signatures of persistent food allergy

Early life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood

Research

The impact of respiratory viruses on lung health after preterm birth

The aim of this review is to highlight the risk factors that may contribute to increased susceptibility to viral respiratory infections among preterm infants

Research

Antibiotics versus topical antiseptics for chronic suppurative otitis media

To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media.

Research

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages

Research

Study protocol for a self-controlled cluster randomised trial of the Alert Program to improve self-regulation and executive function in Australian Aboriginal children

This trial is evaluating the effectiveness of an Alert Program school curriculum for improving self-regulation and executive function in children living in remote Australian Aboriginal communities

Research

The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes

We examined the hypothesis that elevation in urinary (ACR) in adolescents with type 1 diabetes is associated with RVG phenotypes.