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Research

Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkers

Genomewide expression profiling approach identified a comprehensive set of candidate biomarkers with pan-cancer potential

Research

Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age

There was no overall association between delayed DTaP and food allergy; however, children with delayed DTaP had less eczema and less use of eczema medication

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Environmental microbial exposure and protection against asthma

This article looks at the clinical implications of the research into microbial exposure & protection against asthma.

Research

Human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine for the prevention of cervical cancer and HPV-related diseases

HPV-16/18 AS04-adjuvanted vaccine reduces HPV-16/18 infection and associated cervical endpoints in women regardless of age, location, or sexual experience

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Undiagnosed Diseases Network International (UDNI): White paper for global actions to meet patient needs

This white paper discusses the global progress in understanding novel diseases with the aim of encouraging more collaboration between international...

Research

Neighbourhood characteristics and the rate of identification of young people at ultra-high risk for psychosis

This study aimed to determine if the rate of identification of young people at ultra-high risk for psychosis was associated with the level of social deprivation

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Candidate gene analysis supports a role for polymorphisms at TCF7L2 as risk factors for type 2 diabetes in Sudan

Multiethnic associations between T2D and SNPs at TCF7L2, CAPN10 and HHEX extend to Sub-Saharan Africa, specifically Sudan

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Not just "A walking the dog": Dog walking and pet play and their association with recommended physical activity among adolescents

To examine the role of pet play and dog walking in children's and adolescents' leisure time, and the relationship between these activities and physical activity

Research

Optimization is required when using linked hospital and laboratory data to investigate respiratory infections

Despite a recommendation for microbiological testing, only 45% of children hospitalized for respiratory infections in our previous data linkage study linked...

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Impact of prenatal screening and diagnostic testing on trends in Down syndrome births and terminations in Western Australia 1980 to 2013

To assess how prenatal screening and diagnostic testing have impacted the diagnosis, termination and birth prevalence of Down syndrome in Western Australia...