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Impact of Hybrid Closed Loop Therapy on Hypoglycemia Awareness in Individuals with Type 1 Diabetes and Impaired Hypoglycemia AwarenessThis study evaluated the efficacy of using a hybrid closed loop system in restoring hypoglycemia awareness in individuals with impaired awareness of hypoglycemia. Participants with IAH (Gold score ≥4) were recruited into a randomized crossover pilot study.
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The prevalence of tuberculosis, malaria and soil-transmitted helminth infection in minority indigenous people of Southeast Asia and the Western Pacific: protocol for a systematic review and meta-analysisInfectious diseases such as tuberculosis (TB), malaria and soil-transmitted helminthiasis continue to impose a significant global health burden and socio-economic impact. Globally, minority indigenous people are disproportionately affected by poverty and are shown to experience a disparate burden of disease and poorer health outcomes than the comparative majority population.
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Early surveillance of infants and preschool children with cystic fibrosisSensitive and non-invasive surveillance tools are needed for the clinical management of infants and preschool children with cystic fibrosis (CF). The lung clearance index from the multiple breath washout and functional and morphological outcomes from magnetic resonance imaging provide promising alternatives to current gold standard techniques. Early detection and treatment of lung disease during this important period offers the opportunity to improve the quality of life for individuals with CF.
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The longitudinal relationship between BOLD signal variability changes and white matter maturation during early childhoodIntra-individual transient temporal fluctuations in brain signal, as measured by fMRI blood oxygenation level dependent (BOLD) variability, is increasingly considered an important signal rather than measurement noise.
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In utero hypertensive diseases and cognition in offspring into old ageHypertensive diseases of pregnancy including gestational hypertension and preeclampsia continue to pose a major obstetric risk,...
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Is Streptococcus pyogenes resistant or susceptible to trimethoprim-sulfamethoxazole?Streptococcus pyogenes is commonly believed to be resistant to trimethoprim-sulfamethoxazole (SXT), resulting in reservations about using SXT for skin and...
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Alcohol and pregnancy: Do abstinence policies have unintended consequences?A recent study found that while few women reported alcohol as the reason for seeking an abortion, in almost all cases where alcohol was the reason, the women...
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Locally derived traffic-related air pollution and fetal growth restriction: a retrospective cohort studyFetal growth restriction has been inconsistently associated with maternal exposure to elevated levels of traffic-related air pollution.
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Cytokine responses to novel antigens in a peri-urban population in Brazil exposed to Leishmania infantum chagasiVisceral leishmaniasis (VL) is fatal if untreated, and there are no vaccines for this disease
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Nasopharyngeal carriage of Streptococcus pneumoniae: prevalence and risk factors in HIV-positive children in TanzaniaPneumococcal colonization of the nasopharynx is especially common in young children and is a pre-requisite for pneumococcal disease...