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CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangementsIdentified CCI-007 as a novel small molecule that displays rapid toxicity towards a subset of MLL-r, CALM-AF10 and SET-NUP214 leukemia cell lines
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Theory-Based Design and Development of a Socially Connected, Gamified Mobile App for Men About Breastfeeding (Milk Man)The development of Milk Man followed a best practice approach, including the involvement of a multidisciplinary team and grounding in behavior change theory
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Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-upThis study found that differences in regional grey matter volume are discernible at an early stage of ultra-high risk psychosis
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Trends in smoking rates by level of psychological distress-time series analysis of US national health interview survey data 1997-2014People with mental health problems have high rates of smoking, and represent a large proportion of adult smokers in the United States.
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Bile signalling promotes chronic respiratory infections and antibiotic toleranceBile acid signalling is a leading trigger for the development of chronic phenotypes underlying the pathophysiology of chronic respiratory disease
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From Authoritarianism to Advocacy: Lifestyle-Driven, Socially-Transmitted Conditions Require a Transformation in Medical Training and PracticeHere, we open a dialogue on authoritarianism in westernized medicine as a starting point in order to encourage the development of critical research
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Efficacy of the Aussie Optimism Program: Promoting Pro-social Behavior and Preventing Suicidality in Primary School Students. A Randomised-Controlled TrialAussie Optimism Program with teacher training along with coaching may have the potential to positively impact on suicidality and pro-social behavior in the pre-adolescent years
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Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical ResearchWe outline three scenarios from across the health spectrum where issues with health informatics are exemplified.
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Paediatric antimicrobial stewardship and safe prescribing: An assessment of medical staff knowledge and behaviourParticipants demonstrated a good understanding of safe prescribing and antimicrobial stewardship
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Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristicsHere, we show that conditionally reprogrammed airway epithelial cells (CRAECs) can be established from both healthy and diseased phenotypes.