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Meet Jordeana - STARS Award RecipientJordeana Howard is a proud Yawuru, Nyul Nyul & Kija woman from the areas of Broome, Beagle Bay & Alice Downs, and a recipient of a The Kids Research Institute Australia STARS Award.
News & Events
Hopscotch 7th April 2022: The next generation of cancer treatmentsOur first Hopscotch event of 2022 explored exciting new frontiers of cancer treatments happening in the WA Kids Cancer Centre.
News & Events
Marianne & Brad’s gift of giving‘Tis the season of giving. Unconditional giving means you directly power all our research to help more kids live happier, healthier lives.
We are grateful to our many generous friends who support the Institute through philanthropy.
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For pregnant Aboriginal women living in WA’s East Pilbara, significant issues systematically impede their pregnancy journey and a safe and healthy start to life for their babies.
Research
The perspectives of autistic adolescents and their parents on sleep strategies for insomniaAutistic adolescents are vulnerable to sleep difficulties, with up to 80 % experiencing sleep problems, most commonly insomnia. Little is known about how autistic adolescents are involved in their own sleep treatment, and their depth of knowledge about their sleep difficulties. The aims of this study were to investigate autistic adolescent and parent perspectives of experiencing and managing insomnia, and what factors influence the development of these perspectives on insomnia and treatment.
Research
Atopy-related immune profiles are subject to genetic influence as evaluated using school-aged twin pairsThe interaction of genetic and environmental contributions to immunological traits and their association with atopic disease remain unclear. Flow cytometry and in vitro cytokine responses were used to characterize immune profiles from 93 school-aged twin pairs. Using an established twin pair analytical strategy, the genetic and environmental influences on immunological traits were evaluated, along with their association with atopy. Our findings suggest strong genetic influence on several traits, particularly B cell abundance. In contrast, cytokine responses from in vitro stimulations appeared mainly shaped by environmental exposures.
Research
Caregivers' Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online SurveyCyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is an ultrarare genetic condition causing developmental epileptic encephalopathy characterized by seizures and motor and intellectual disabilities. No disease-modifying therapies are available, and treatments focus mainly on symptom management to improve quality of life.