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Research
Tapasin assembly surveillance by the RNF185/Membralin ubiquitin ligase complex regulates MHC-I surface expressionImmune surveillance by cytotoxic T cells eliminates tumor cells and cells infected by intracellular pathogens. This process relies on the presentation of antigenic peptides by Major Histocompatibility Complex class I (MHC-I) at the cell surface. The loading of these peptides onto MHC-I depends on the peptide loading complex (PLC) at the endoplasmic reticulum (ER).
Research
Rationale for use for monoclonal antibody and anti-cytokine therapy for multisystem inflammatory syndrome in children: A systematic reviewObjective: To review systematically the rationale for choice and use of monoclonal antibody and anti-cytokine therapy in multisystem inflammatory syndrome in children.
It’s a brave move to upend your entire family to seek a fresh start – or safety – in a new country: even braver when the country you’re moving to has a completely different language, structure and cultural outlook.
A world-first study led by Dr Aveni Haynes at The Kids’ Rio Tinto Children’s Diabetes Centre, is helping to detect early changes in blood sugar levels.
A unique initiative is combining research, action and advocacy to deliver evidence- based improvements to the health and wellbeing of Aboriginal families in Perth and Western Australia’s north west.
Three hundred and fifty million people live with an undiagnosed disease worldwide and three quarters of them are children.
Flow cytometry is a technology used to measure complex cell phenotype and functions. Our Flow Facility is equipped with 3 flow cytometers/analysers, one...
A The Kids Research Institute Australia study has found the average six-month-old Australian baby has more than one hour of screen time each day.
An Australian-first study, funded by Perth Children's Hospital Foundation, demonstrating the effectiveness of a new immunisation against respiratory syncytial virus (RSV) for babies found it to be almost 90 per cent effective in reducing hospitalisation rates.
When Perth mum Lacy Swan’s daughter Charlotte failed the newborn hearing test at 3 days of age, the medical team explained it could simply be due to fluid on the ears.