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Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter UsageThis study helps us understand how cancer cells are regulated by key genes and their corresponding networks to alter their fate in response to specific...
Research
A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinomaIn this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from...
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GFP-complementation assay to detect functional CPP and protein delivery into living cells.Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell...
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Patterns of depressive symptoms and social relating behaviors differ over time from other behavioral domains for young people with Down syndromePeople with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general...
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Can skin exposure to sunlight prevent liver inflammation?Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD.
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Mechanisms of allergic disease - environmental and genetic determinants for the development of allergyEnvironmental exposures including maternal inflammation, diet, nutrient balance, microbial colonization and toxin exposures can directly and indirectly...
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Environmental health challenges in remote Aboriginal Australian communities: clean air, clean water and safe housingA considerable health disparity exists between Aboriginal and non-Aboriginal Australians, including a higher incidence and severity of cardiovascular and...
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The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stageAlthough debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment...
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Contrasting effects of prenatal life stress on blood pressure and bodymass index in young adultsThe effect of prenatal life stress on BP was accentuated by a higher BMI. Fetal programming events as a result of prenatal stress may underpin some of these...
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What works in preventing suicide in Aboriginal and Torres Strait Islander Communities: preliminary findingsSuicide, suicide ideation and self-harm are critically important public health issues for Aboriginal and Torres Strait Islander communities.