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Sialic acid-to-urea ratio as a measure of airway surface hydrationWe explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content.
Research
Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteinsPhylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited
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ANRIL Promoter DNA Methylation: A Perinatal Marker for Later AdiposityExperimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes.
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There is variability in the attainment of developmental milestones in the CDKL5 disorderIndividuals with the CDKL5 disorder have been described as having severely impaired development.
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DNA Methylation Profiles of Airway Epithelial Cells and PBMCs from Healthy, Atopic and Asthmatic ChildrenAllergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis.
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Health professionals' perceptions about the adoption of existing guidelines for the diagnosis of fetal alcohol spectrum disorders in AustraliaDespite the availability of five guidelines for the diagnosis of fetal alcohol spectrum disorders (FASD), there is no national endorsement for their use in...
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Assisted reproductive technology and major birth defects in Western australiaThe object of this work was to estimate the prevalence of major birth defects diagnosed by 6 years of age in all births and terminations of pregnancy for...
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Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic AzithromycinDysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured...
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Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from MozambiqueDespite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show primary...
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Prevention of neural tube defects with folateA programme of monitoring mandatory fortification has been established in Australia.