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Disruption of ovarian function and induction of apoptosis in female mice by Brefeldin A: Mechanistic insights into reproductive toxicity

The investigation of ovarian development, dysfunction, and aging is essential for female reproductive health. Despite extensive research on the cellular functions of Brefeldin A (BFA) as an intracellular transport inhibitor, its specific effects and mechanisms on ovarian development/aging remain inadequately understood.

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

The antirelapse efficacy of primaquine is related to the total dose administered, whereas the risks of haemolysis and gastrointestinal intolerance are associated with the daily dose administered. National Malaria Control Programmes require local information on efficacy, tolerability and safety to optimize antimalarial treatment policies for Plasmodium vivax malaria control and elimination efforts.

Who gets asthma, and why?

Citation: Evans DJ, D Sly PD, Foster P, Donovan C. Who gets asthma, and why? Med J Aust. 2025;223(S10):S19-S23. Keywords: Asthma; Lung diseases;

Bullying

Bullying is now regarded as a health problem and not just a disciplinary problem. Increasing evidence shows both traditional bullying (e.g. hitting, teasing) and cyberbullying have lasting effects on young people (both those who bully and those who are bullied), including damage to self-esteem, academic results and mental health.

Multigenerational Familial and Environmental Risk for Autism (MINERvA) Network

The MINERvA Network will allow more accurate and precise determination of the contributions of familial and environmental factors to the etiology of autism.

Djaalinj Waakinj leads to better hearing – and happier kids

An innovative The Kids program is helping to slash waiting times so children can have their ear problems checked within days.

Inching towards answers for children with ultra-rare CDKL5

The Kids Research Institute Australia is helping scientists across the globe inch their way towards clinical trials which could, at last, provide relief for children and families dealing with CDKL5.

Pandemic pivot keeps vital skin program alive

Hip Hop 2 SToP video It didn’t take long for shyness to make way for excitement when a group of children from Dampier Peninsula communities got

Push to catch beneath-the-radar newborn virus

The Kids researchers are working with Perth Children’s Hospital and other experts across the country to get ahead of a sneaky virus few mums or even health professionals have heard of.

How traditional bush tucker could help boost Aboriginal children’s vitamin D

Researchers are collaborating with Community Elders to find out how bush tucker and traditional food can improve the health of Aboriginal children.