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Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent mannerOur data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma development
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Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case seriesThe promotion of a low carbohydrate diet in media is in contrast to published pediatric diabetes guidelines that endorse a balanced diet from a variety of foods
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Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumCurrently, DNA methylation is the most studied epigenetic phenomenon in large populations
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Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd EditionThe realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence.
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Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in childrenCombining elevated CRP with the presence or absence of clinical signs/ symptoms differentiates definite bacterial from presumed viral pneumonia better than CRP alone
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Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic ResponseThe functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target
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Improving delivery of secondary prophylaxis for rheumatic heart disease in a high-burden setting: Outcome of a stepped-wedge, community, randomized trialThis strategy did not improve adherence to rheumatic heart disease secondary prophylaxis within the study time frame.
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High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitisHigh dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis
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Out-of-Home Care and the Educational Achievement, Attendance, and Suspensions of Maltreated Children: A Propensity-Matched StudyOut-of-home care was not found to be a significant factor in the adverse educational outcomes of these children
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Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometryWe describe a cost-effective tag single nucleotide polymorphism approach using a multiplexed genotyping assay with mass spectrometry