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Delivering smart drugs into cells

The Drug Discovery Unit has been finding ways for smart drugs to penetrate deep into cells and attacking their disease targets while causing fewer side effects

The Kids researchers awarded Raine Medical Research Foundation funding

Congratulations to three The Kids Research Institute Australia researchers, who have been awarded funding from the Raine Medical Research Foundation.

Three new Board appointments at The Kids

Perth's The Kids Research Institute Australia is excited to announce the appointment of Professor Alex Brown, Ms Nicole O'Connor and Professor Jozef Gecz to its Board.

A pathogenic role for the integrin CD103 in experimental allergic airways disease

Role for CD103 in the pathogenesis of experimental allergic airways disease in BALB/c mice through local control of CD4+ T cell and DC subset recruitment

Prior human papillomavirus-16/18 AS04-adjuvanted vaccination prevents recurrent high grade cervical intraepithelial neoplasia after definitive surgical therapy

Women who undergo surgical therapy for cervical lesions after vaccination with the HPV-16/18 vaccine may continue to benefit from vaccination

High burden of RSV hospitalization in very young children: a data linkage study

RSV was associated with substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and pre-term children

Declining rates of sterilization procedures in Western Australian women from 1990 to 2008: The relationship with age, hospital type, and government policy changes

Rates of female sterilization procedures in Western Australia have declined substantially across all age groups in the last two decades

Impaired airway epithelial cell responses from children with asthma to rhinoviral infection

Human rhinovirus infection delays repair and inhibits apoptotic processes in epithelial cells from non-asthmatic and asthmatic children

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15

Safety and immunogenicity of a booster dose of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults: A randomized phase 1 study

Immune responses after the initial vaccination persisted for the 12 months studied, with little additional response after the booster dose at 6 months