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Research

Involving young people with lived experience in advancing mental health science: an exploratory qualitative study from Pakistan and India

Meaningful involvement of young People with Lived Experience (PWLE) in co-designing youth mental health interventions has been much emphasized globally. However, there is a scarcity of evidence on involving PWLE of mental health problems in designing, implementing and evaluating mental health interventions, especially in Low- and Middle-Income Countries.

Research

Twenty-five is not a neurobiologically determined age of maturity for gender-affirming medical decision-making

Among the increasing threats to the healthcare of transgender and gender-diverse people globally, are efforts to deny gender-affirming medical care to people under age 25 typically justified by stating that the human brain is not developed until the mid-to-late 20's. Thus, this line of reasoning states young adults are not sufficiently mature to be responsible for autonomous healthcare decision-making— at least in regard to gender-affirming care.

Research

MetaNeb Versus Usual Care During Exacerbations of Cystic Fibrosis: An RCT

During exacerbations, when symptom and treatment burden are increased, individuals with cystic fibrosis (CF) are likely to prefer airway clearance techniques (ACTs) that require minimal effort. Therefore, in adults with CF who were hospitalised with an exacerbation, we sought to compare the effect of the MetaNeb with usual ACTs on respiratory function and expectorated sputum.

Research

A microRNA-based dynamic risk score for type 1 diabetes

Identifying individuals at high risk of type 1 diabetes (T1D) is crucial as disease-delaying medications are available. Here we report a microRNA (miRNA)-based dynamic (responsive to the environment) risk score developed using multicenter, multiethnic and multicountry ('multicontext') cohorts for T1D risk stratification. Discovery (wet and dry lab) analysis identified 50 miRNAs associated with functional β cell loss, which is a hallmark of T1D. 

Laboratory Technologies

Within the Institute, we have a commitment to the highest standards of research with pro-active staff ensuring the lab environment is safe and secure.

Flow Facility

Flow cytometry is a technology used to measure complex cell phenotype and functions. Our Flow Facility is equipped with 3 flow cytometers/analysers, one...

RSV hospitalisation admissions slashed by new immunisation program

An Australian-first study, funded by Perth Children's Hospital Foundation, demonstrating the effectiveness of a new immunisation against respiratory syncytial virus (RSV) for babies found it to be almost 90 per cent effective in reducing hospitalisation rates.

Rainbow roadmap a source of Indigenous pride

Alarming statistics laying bare the social emotional wellbeing and mental health challenges facing Aboriginal and Torres Strait Islander LGBTQA+ youth are driving a multi-partner program to provide them with greater support.

Research

Cybersafety

Even in the safety of their home, there are many risky places a child or teenager can visit online. This can be due to the content they see, who they come into contact with, and personal information they share.

Research

Fetal Alcohol Spectrum Disorder (FASD)

Fetal Alcohol Spectrum Disorder (FASD) is a lifelong condition characterised by severe neurodevelopmental impairment due to prenatal exposure to alcohol.