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Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors
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Early respiratory viral infections in infants with cystic fibrosisEarly viral infections were associated with greater neutrophilic inflammation and bacterial pathogens
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Spatial patterns of tuberculosis and HIV coinfection in EthiopiaOur study provides evidence for geographic clustering of tuberculosis/human immunodeficiency virus co-infection in Ethiopia
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Bowel patterns, gastrointestinal symptoms, and emotional well-being in adolescents: A cohort studyIn adolescents, bowel patterns and gastrointestinal symptoms are diverse and show sex differences
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Towards the development of an integrative, evidence-based suite of indicators for the prediction of outcome following mild traumatic brain injuryPerformance on neuropsychological measures may be useful for predicting persisting post-concussion symptoms
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Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma modelWe established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model
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Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma developmentType 1 and 3 interferon response capacity appears strongly developmentally constrained at birth
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Evaluation of a phased pneumococcal conjugate vaccine introduction in Mongolia using enhanced pneumonia surveillance and community carriage surveysStreptococcus pneumoniae causes substantial morbidity and mortality among children. The introduction of pneumococcal conjugate vaccines (PCV) has the potential to dramatically reduce disease burden. As with any vaccine, it is important to evaluate PCV impact, to help guide decision-making and resource-allocation.
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Use of Continuous Glucose Monitoring Trends to Facilitate Exercise in Children with Type 1 DiabetesThis study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity
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Insights into respiratory disease through bioinformaticsHere, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases