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Beacon of hope for navigating online world

In a world where TikTok dances and Minecraft adventures take centre stage, kids are spending more time online than ever before.

RHD Endgame tantalisingly close

Professor Jonathan Carapetis has made eliminating rheumatic heart disease his life’s work.

Rapid-fire research the latest weapon in war on junk food ads

A new rapid research funding model is translating into quick results.

How the pandemic has shaped the mental health of our kids

Researchers went into 79 WA primary and secondary schools in 2020 and found increased levels of emotional distress among students and families.

What’s in a name?

For thousands of WA children living with undiagnosed diseases, it’s hope.

Standing up to a cruel DISEASE

Klair Bayley knew her son Logan would eventually need a wheelchair.

Country-level and global burden of diseases caused by group A Streptococcus: protocol for a multicountry epidemiological study

Group A Streptococcus (Strep A) causes a wide spectrum of diseases, ranging from pharyngitis and impetigo to severe invasive infections and immune-mediated conditions such as acute rheumatic fever, rheumatic heart disease and acute post-streptococcal glomerulonephritis. Contemporary data on the global burden of Strep A diseases are lacking.

Conservation of gene expression patterns between the amniotic and nasal epithelium at birth

Amniotic epithelial cells are fetal-derived stem cells, capable of differentiating into all three germ layers, including mature epithelial cell populations. Here, we hypothesised that the amniotic epithelium might serve as a surrogate tissue source for investigating transcriptional profiles in the respiratory epithelium of newborns.

Beyond bone: the emerging role of osteoclasts in immune regulation, leukemia development and following myeloablative therapy

Osteoclasts are important regulators of bone remodeling, with an established role in maintaining skeletal homeostasis. The emergence of osteoimmunology has identified osteoclasts as key players in the immune system. In particular, osteoclasts can initiate bi-directional crosstalk mechanisms with hematopoietic stem cells and various immune cells, such as T cells, B cells and NK cells, to influence hematopoiesis and inflammatory response.

A primary cell model of the very preterm epithelium reveals barrier defects at 1 year of age

Limited evidence suggests that airway epithelial structure and function is disrupted in very preterm infants; however, the epithelial morphology and physiology has not been well characterised following discharge from neonatal intensive care. This study aimed to characterise the nasal airway epithelium from 1-year-old survivors of very preterm birth.