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An introduction to clinical trial designThis manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches
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An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorderOverall, we found that the regulatory variants in autism spectrum disorder cases were enriched in ASD-risk genes and genes involved in fetal neurodevelopment
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Environmental enrichment intervention for Rett syndrome: An individually randomised stepped wedge trialWe investigated the effects of environmental enrichment on gross motor skills and blood BDNF levels in girls with Rett syndrome.
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Maternal alcohol disorders and school achievement: a population cohort record linkage study in Western AustraliaChildren of mothers with alcohol use disorders are at risk of not meeting minimum educational benchmarks in numeracy and literacy, with the risk highest among Indigenous children.
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Effect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosisBackground: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease.
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Analysis of expression of FLI1 and MMP1 in American cutaneous leishmaniasis caused by Leishmania braziliensis infectionMMP1 is regulated by factors other than FLI1, and that the influence of IL-6 on MMP1 was independent of its effect on FLI1 in Leishmania braziliensis
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Association Between Family Characteristics and the Effect of Timing of Regular Egg Introduction in Infant Egg AllergyA recent systematic review of 5 randomized clinical trials, found that early egg introduction was associated with reduced egg allergy.
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The psychosocial burden of childhood overweight and obesity: evidence for persisting difficulties in boys and girlsOverweight and obese children reported greater psychosocial distress than healthy weight children, and these differences were more pronounced for girls than boys.
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Australian children living with rare diseases: experiences of diagnosis and perceived consequences of diagnostic delaysParents of children living with rare chronic and complex diseases have called for better education and resourcing of health professionals
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Maternal dietary intake in pregnancy and lactation and allergic disease outcomes in offspringAs the prevalence of allergic disease dramatically rises worldwide, prevention strategies are increasingly being considered.