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Research

Insights into the associations between the gut microbiome, its metabolites and heart failure

Heart failure (HF) is the end stage of most cardiovascular diseases and remains a significant health problem globally. We aimed to assess whether patients with left ventricular ejection fraction ≤45% had alterations in both the gut microbiome profile and production of associated metabolites when compared to a healthy cohort.

Research

Understanding the role of microbiota in cancer

This chapter provides an update on the latest findings in the role of the gut microbiota in cancer. Herein we discuss how the composition and the diversity of the gut microbiota result in the latter to function as a tumour-suppressor, a tumour-promoter or an aid in the recovery post cancer treatment. © 2023 John Wiley & Sons Ltd. All rights reserved.

Research

A pilot study to develop assessment tools for Group A Streptococcus surveillance studies

Group A Streptococcus (GAS) causes pharyngitis (sore throat) and impetigo (skin sores) GAS pharyngitis triggers rheumatic fever (RF) with epidemiological evidence supporting that GAS impetigo may also trigger RF in Australian Aboriginal children. Understanding the concurrent burden of these superficial GAS infections is critical to RF prevention. This pilot study aimed to trial tools for concurrent surveillance of sore throats and skins sore for contemporary studies of RF pathogenesis including development of a sore throat checklist for Aboriginal families and pharynx photography.

Research

Australian researchers oppose funding from the Foundation for a Smoke-Free World

Research and research funding must be independent of the tobacco industry, which continues to cause so much suffering

Research

A marked shift in innate and adaptive immune response in chinese immigrants living in a western environment

There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years

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Intellectual disability in children conceived using assisted reproductive technology

The risk of intellectual disability was increased in children born after assisted reproductive technology in Western Australia from 1994 to 2002

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Insights into respiratory disease through bioinformatics

Here, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases

Research

Explaining the evolution of ethnicity differentials in academic achievements: The role of time investments

This paper is the first to explore whether differences in time use by children of Asian-born parents may help to explain the observed differentials in school achievements

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Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

Higher maternal pre-pregnancy BMI and gestational weight gain were associated with an increased risk of childhood overweight/obesity

Research

Predicting respiratory hospital admissions in young people with cerebral palsy: A 3-year longitudinal study using linked data

Early identification of oropharyngeal dysphagia and the management of seizures may help prevent serious respiratory illness